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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD4
All Species:
13.33
Human Site:
S288
Identified Species:
26.67
UniProt:
Q9Y227
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y227
NP_001122402.1
616
70255
S288
Y
E
V
P
K
T
V
S
F
A
S
S
Q
Q
E
Chimpanzee
Pan troglodytes
XP_519659
710
80224
A382
G
G
V
S
T
Q
I
A
Y
E
V
P
K
T
E
Rhesus Macaque
Macaca mulatta
XP_001108472
728
82237
A400
G
G
V
S
T
Q
I
A
Y
E
V
P
K
T
E
Dog
Lupus familis
XP_543243
608
69462
A280
G
G
V
S
T
Q
I
A
Y
E
V
P
K
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT4
613
69727
S288
Y
E
V
P
Q
T
V
S
F
A
S
S
Q
Q
E
Rat
Rattus norvegicus
P97687
511
57389
I199
E
Q
S
W
L
N
F
I
S
D
S
Q
K
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
S304
Y
E
V
P
K
T
V
S
F
A
S
S
H
Q
E
Chicken
Gallus gallus
P79784
495
54515
L183
N
F
I
K
R
G
W
L
G
E
W
I
Q
S
K
Frog
Xenopus laevis
NP_001088548
616
70594
S288
Y
E
V
P
K
S
V
S
F
A
S
S
Q
Q
E
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
A280
G
G
V
S
T
Q
I
A
Y
E
V
P
K
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
I240
S
S
I
N
V
E
N
I
N
L
G
C
R
E
D
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
N224
V
Y
A
W
I
G
I
N
Y
V
L
G
R
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
82.2
93.5
N.A.
93
26.4
N.A.
86.5
24.5
77.1
70.6
N.A.
N.A.
N.A.
30.6
48.5
Protein Similarity:
100
85.4
82.8
96.4
N.A.
97.5
47.4
N.A.
92
42.6
88.4
84.2
N.A.
N.A.
N.A.
48.8
63.3
P-Site Identity:
100
13.3
13.3
13.3
N.A.
93.3
13.3
N.A.
93.3
6.6
93.3
13.3
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
40
40
40
N.A.
100
26.6
N.A.
93.3
26.6
100
40
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
34
0
34
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
17
% D
% Glu:
9
34
0
0
0
9
0
0
0
42
0
0
0
9
67
% E
% Phe:
0
9
0
0
0
0
9
0
34
0
0
0
0
9
0
% F
% Gly:
34
34
0
0
0
17
0
0
9
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
17
0
9
0
42
17
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
25
0
0
0
0
0
0
0
42
0
9
% K
% Leu:
0
0
0
0
9
0
0
9
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
9
9
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
0
0
0
0
0
0
0
34
0
0
0
% P
% Gln:
0
9
0
0
9
34
0
0
0
0
0
9
34
42
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
17
0
0
% R
% Ser:
9
9
9
34
0
9
0
34
9
0
42
34
0
9
0
% S
% Thr:
0
0
0
0
34
25
0
0
0
0
0
0
0
34
0
% T
% Val:
9
0
67
0
9
0
34
0
0
9
34
0
0
0
0
% V
% Trp:
0
0
0
17
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
34
9
0
0
0
0
0
0
42
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _